She started her career after memorizing the telephone number of a local tennis clinic from an advertisement.During the NATO bombing of Yugoslavia, she was forced to train during the morning to avoid bombardments.
When she was 15, Ivanovic spent four hours in a locker room crying after a defeat – the first that her new manager had witnessed.
She thought that Dan Holzmann, the manager in question, would abandon her, thinking her not good enough to become a professional tennis player. In 2004, she went 26–0 on the ITF circuit, and won all five events that she entered, two of them as a qualifier.
As a qualifier in Zürich, she overcame a 5–1 third set deficit along with two match points to defeat world No. She then debuted in the qualifying draw of a Major at the US Open, where she was defeated by Lioudmila Skavronskaia after winning the first set 6–1 and having two match points in the 3rd set.
Competing as a professional since 2003, Ivanovic has won 15 WTA Tour singles titles, including one Grand Slam singles title.
As of 2016, she has career earnings of over $15 million.